Hochkonjunktur für Radiotracer
نویسندگان
چکیده
منابع مشابه
Radiotracer Imaging of Peripheral Vascular Disease.
Peripheral vascular disease (PVD) is an atherosclerotic disease affecting the lower extremities, resulting in skeletal muscle ischemia, intermittent claudication, and, in more severe stages of disease, limb amputation and death. The evaluation of therapy in this patient population can be challenging, as the standard clinical indices are insensitive to assessment of regional alterations in skele...
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Monoamine oxidase (MAO) oxidizes amines from both endogenous and exogenous sources thereby regulating the concentration of neurotransmitter amines such as serotonin, norepinephrine, and dopamine as well as many xenobiotics. MAO inhibitor drugs are used in the treatment of Parkinson's disease and in depression stimulating the development of radiotracer tools to probe the role of MAO in normal hu...
متن کاملA Philosophy for CNS Radiotracer Design
Decades after its discovery, positron emission tomography (PET) remains the premier tool for imaging neurochemistry in living humans. Technological improvements in radiolabeling methods, camera design, and image analysis have kept PET in the forefront. In addition, the use of PET imaging has expanded because researchers have developed new radiotracers that visualize receptors, transporters, enz...
متن کاملMonoamine oxidase: radiotracer development and human studies.
Monoamine oxidase (MAO) is an integral protein of outer mitochondrial membranes and occurs in neuronal and nonneuronal cells in the brain and in peripheral organs. It oxidizes amines from both endogenous and exogenous sources, thereby influencing the concentration of neurotransmitter amines as well as many xenobiotics. It occurs in two subtypes, MAO A and MAO B, which are different gene product...
متن کاملVariables in Radiotracer Kinetics and Biodistributions
It is possible, several hundred years later, to have some sympathy with Alfonso X when he protested the complexity of the world, even as it was perceived in the Middle Ages. If nuclear medicine practice was simple, in any given patient, the injection of a radiotracer might result in scintigraphic images that are either normal or abnormal. In the latter case disease will be present. The reality ...
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ژورنال
عنوان ژورنال: Im Focus Onkologie
سال: 2017
ISSN: 1435-7402,2192-5674
DOI: 10.1007/s15015-017-3279-x